RNAi_safe

Safety of RNAi technology in plant protection: Method evaluation for estimating effectivity and potential impacts on target and off-target organisms

Term

2022-01-01 bis 2026-02-15

Project management

• Torsten, Will
• Christoph, Joachim

Responsible institute

Institut für Pflanzenschutz in Ackerbau und Grünland

Project preparer

• Khalid, Amari
• Antje, Dietz-Pfeilstetter
• Torsten, Will
• Christoph, Joachim
• Silvio, Erler

Cooperation partner

• Institut für Phytomedizin
• Institut für Bienenschutz (JKI)
• Institut für die Sicherheit biotechnologischer Verfahren bei Pflanzen (JKI)
• Institut für Resistenzforschung und Stresstoleranz (JKI)

Overall objective of the project

“RNAi_safe” pursues a methodological approach to answer open questions about the sage use of RNAi technology in plant protection. The project aims at detecting and evaluating potential exposure pathways and effects of dsRNA-based plant protection products on target organisms (long-term effects), crops (secretion, depot formation) and the extended food web (off-target organisms). Further, it will help in developing expertise to evaluate methods for assessing plant protection products, using RNAi technology as mode of action. Finally, existing methods for assessing dsRNA-based plant protection products in the risk assessment will be developed and evaluated.

Funder

Federal Ministry of Agriculture, Food and Regional Identity