Recent biological research methods produce an increasing amount of experimental data. In the last years, the complex analyses of such data resulted in an increased demand for interdisciplinary science denoted as computational biology. Computational biology comprises, for instance, sequence analysis, pattern recognition, image processing, data management and data integration. At JKI, the colleagues in the field of computational biology support the researchers in 17 specific institutes working in the field of molecular genetics.
The main focus is sequence analysis and especially the work with sequence data in the field of Next Generation Sequencing, where millions of small DNA fragments have to be analyzed. It is infeasible to carry out such analyses by hand. Hence, specialized bioinformatics tools have to be used semi-automatically. Furthermore, the necessary computer technology exceeds in most cases the capacity of conventional workstations. Therefore, the computational power is provided by the computational biology group in cooperation with the central IT of the JKI.
These activities are supplemented by specific research on sequence analysis and genome annotation and genome-wide association mapping.