Within the scope of these cooperations (universities, other research institutes), the focus lies on the determination of individual active ingredients as well as the multi-component screening for the investigation center for bee poisoning (current status: about 290 substances) in bees and bee-relevant matrices (plants, pollen, nectar, wax, honey, bee larvae). Samples are taken from laboratory and (semi-)field experiments within the scope of defined research questions. The questions include the determination of residues in honey and wild bees and the samples come, for example, from experiments carried out at selected sites with varying degrees of agricultural use. The main objective is to determine residue loads in matrices mentioned earlier, and, if necessary to make recommendations to reduce them.